What are the side effects of zoledronic acid injection?

What are the side effects of zoledronic acid injection?

The following side effects are common (occurring in greater than 30%) for patients taking zoledronic acid:

  • Ostealgia.
  • Nausea.
  • Fever usually mild and short lived.
  • Fatigue.
  • Anemia.
  • Vomiting.
  • Constipation.
  • Flu-like symptoms; mild fever sometimes accompanied by malaise, chills, fatigue and flushing.

How long do the side effects of zoledronic acid infusion last?

The majority of the side effects, such as fever and chills, pain in the muscles or joints, and headache, occur within the first three days following the dose of Zoledronic acid 5 mg. The symptoms are usually mild to moderate and go away within three days.

What are the negative side effects of Reclast?

Common side effects of Reclast include:

  • nausea,
  • tiredness,
  • flu-like symptoms (e.g., fever, chills, muscle/joint aches),
  • cough,
  • dizziness,
  • headache,
  • vision problems,
  • diarrhea,

What are the side effects of Aclasta?

Less serious Aclasta side effects may include:

  • cough;
  • loss of appetite, nausea, vomiting;
  • diarrhea, constipation;
  • headache, dizziness, tired feeling;
  • low blood pressure, swelling in your legs or feet;
  • bone, joint or muscle pain; or.
  • redness or swelling where the needle was placed.

How many Aclasta infusions can you have?

How often should an Aclasta infusion be given? The suggested frequency varies between physicians. However, for the average patient we recommend giving it at 0, 18, and 36 months (i.e. 3 infusions over a 3 year period.) Occasionally it may be used for longer.

What happens after zoledronic acid infusion?

You may experience a reaction during the first few days after you receive a dose of zoledronic acid injection. Symptoms of this reaction may include flu-like symptoms, fever, headache, chills, and bone, joint or muscle pain.

How long do aclasta side effects last?

The majority of the side effects, such as fever and chills, pain in the muscles or joints, and headache, occur within the first three days following the dose of Aclasta. The symptoms are usually mild to moderate and go away within three days.

How do you feel after Reclast infusion?

“1st infusion of Reclast has left me feeling fatigued with terrible pain and swelling in hands, especially thumb joints that is not improving after nearly two weeks along with overall body aches and pains, headache and difficulty sleeping . I would never consider taking this drug again!”

How long does Aclasta stay in body?

How long treatment will last. For osteoporosis, each dose of Aclasta lasts one year. Your doctor will check your condition and may prescribe further annual doses. For Paget’s disease, each dose of Aclasta may work for longer than one year.

Does Aclasta increase bone density?

Finally, Aclasta was more effective than risedronate at increasing spine bone density over a year’s treatment in patients taking glucocorticoids. In Paget’s disease, Aclasta was more effective than risedronate.

How long can you stay on Aclasta?

Paget’s disease The usual dose is 5 mg, given to you as one initial infusion into a vein by your doctor or nurse. The infusion will take at least 15 minutes. Aclasta may work for longer than one year, and your doctor will let you know if you need to be treated again.

Can you give Aclasta and zoledronic acid together?

The dose of 5 mg zoledronic acid must be administered intravenously over at least 15 minutes. Aclasta contains the same active ingredient found in Zometa (zoledronic acid), used for oncology indications, and a patient being treated with Zometa should not be treated with Aclasta.

How is Aclasta given?

Aclasta is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take at least 15 minutes to complete. Aclasta is sometimes given only once per year.

What are the side effects of Aclasta infusion?

Fever is the most common adverse effect associated with zoledronic acid (the active ingredient contained in Aclasta) infusion. Flu-like syndromes including fever, chills, bone pain, and/or arthralgias and myalgias have also occasionally been reported. These symptoms generally did not require treatment and resolved within 24 to 48 hours.

What are the possible adverse effects of zoledronic acid infusion?

Fever is the most common adverse effect associated with zoledronic acid infusion. Flu-like syndromes including fever, chills, bone pain, and/or arthralgias and myalgias have also occasionally been reported. These symptoms generally did not require treatment and resolved within 24 to 48 hours.