What is dendrimer generation?
3.6. On the basis of growth process of the dendrimers, these can be classified according to their generation number, such as G0.5, G1, G2, G3, G4, and G5. Dendrimers can be synthesized by both divergent and convergent methods.
What are the components of dendrimer?
Dendrimers consist of three parts: a core, an inner shell, and an outer shell. The dendrimer properties are mainly determined by the functional groups on the molecular surface [112–114].
Is dendrimer a nanoparticle?
Introduction. Dendrimers are nano-sized, radially symmetric molecules with well-defined, homogeneous, and monodisperse structure consisting of tree-like arms or branches .
Which of the following is not a component of dendrimer?
3. Which of the following is not a component of dendrimer? Explanation: The dendrimer has three components,i.e. central core, interior dendritic structure and the exterior surface. No stem is present in the dendrimer.
What is Pamam dendrimer?
PAMAM dendrimers are a family of highly branched and mono-disperse synthetic macromolecules with well-defined structures and compositions. Synthesis of these nanocarriers can be carried out through the divergent route.
Which of the following is not the other name of the dendrimer?
Which of the following is not the other name for dendrimers? Explanation: Dendrimers are also known as dendritic, starburst and cascade polymers. Synonymous terms for dendrimer include arborols and cascade molecules. Deluge is not used with dendrimers.
What is a third generation dendrimer?
For example, if a dendrimer is made by convergent synthesis (see below), and the branching reactions are performed onto the core molecule three times, the resulting dendrimer is considered a third generation dendrimer. Each successive generation results in a dendrimer roughly twice the molecular weight of the previous generation.
What are dendrimers and dendrons?
Dendrimers and dendrons are monodisperse and usually highly symmetric, spherical compounds. The field of dendritic molecules can be roughly divided into low- molecular weight and high-molecular weight species.
How are dendrimers synthesized?
Dendrimers can be synthesized by two major approaches. In the divergent approach, used in early periods, the synthesis starts from the core of the dendrimer to which the arms are attached by adding building blocks in an exhaustive and step-wise manner.
What are the advantages of a dendrimer?
Dendrimers are particularly versatile drug delivery devices due to the wide range of chemical modifications that can be made to increase in vivo suitability and allow for site-specific targeted drug delivery.