What is rapid mixer granulator?
A rapid mixer granulator is a high-precision tool used for dry grinding and wet granulation of materials/ingredients in the same tub. High-quality quick mixer granulators are needed to avoid segregation of powder, to prepare material for compression or to enhance flowing characteristics.
What is ampere load in RMG?
What Is Ampere Load In RMG? Ampere load is the current which is used by the chopper and impeller for the rotation of powder or granules. Ampere load is high at the start of the process and then gradually decreases as the load on the motor decreases.
How is RMG capacity calculated?
Claimed capacity is provided by vendor in liters and to calculate capacity in kgs,first calculate bulk density of powder to be mixed and then it is multiplied by capacity in liters. claimed capaciy in liters is 400 liter and bulk density is 0.8 then capacity in kgs is 400*0.8=320kg.
Why RMG is used?
Rapid mixture granulator (RMG) is used in mixing, agitation, and shear mixing (to break internal molecular force). RMG is used in pharmaceuticals to make granules. The components of the RMG (impeller and chopper) are highly responsible for the wet granulation process.
What is end point in RMG?
Endpoint can be defined as a target particle size mean or distribution.
What is impeller speed in RMG?
Speed – 200 RPM (impeller rotates in an anti-clockwise direction).
What is kneading time in RMG?
Dry mixing takes about 3-5 minutes to mix the ingredients, wet mixing takes 5-10 minutes to make the wet mass of material while the granulation process takes 5-10 minutes to make 0.5 mm to 1.5 mm sized granules. Mixing time consumed in processing is depends upon the ingredients quantity and their particle size.
How many stages are there in qualification?
Qualification (DQ) Installation Qualification (IQ) Operational Qualification (OQ) Performance Qualification (PQ)
What is qualification in GMP?
Qualification is a process of assurance that specific system(s), premises or equipment are able to achieve predetermined acceptance criteria to confirm the attributes what it purports to do.
How many sensors are there in RMG?
RMG Real Time Water Level Controller Wired Sensor Security System
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What is torque in RMG?
Torque is a measure of the amount of energy needed to rotate the impeller. Therefore, torque depends on the resistance of the mass against rotation of the impeller (2–4). In the wet mixing process, changes in torque occur as the result of a change in the cohesive force of the granules in the wet powder bed.
What is the use of rapid Mixer granulator?
It is used to mix the pharmaceutical ingredients and make the granules before compression and also called a high shear mixer. Impellers and chopper are mainly responsible for wet granulation in the rapid mixer granulator.
What is a High Shear Mixer granulator?
With a high shear mixer granulator that has an appropriate technology, you will produce granules with the right porosity, shape, density and size. It is this simple, let the manufacturer mention the so called “patented or new technology”.
What is the operational range of the equipment during granulation?
While doing the exercise consideration is given to the operational range of the equipment that is at minimum level (20% of capacity), optimum level (50% of the capacity) and maximum level (80% of the capacity). At the end of the granulation process wet mass is checked for its physical appearance. Product Name :
What is the difference between dry mixing and granulation process?
After the formation of wet mass impeller and chopper are operated at high speed to form the granules of the required size. Dry mixing takes about 3-5 minutes to mix the ingredients, wet mixing takes 5-10 minutes to make the wet mass of material while the granulation process takes 5-10 minutes to make 0.5 mm to 1.5 mm sized granules.