How do you give Vasotec IV?
HOW TO USE: Inject this medication directly into a vein (IV) over 5 minutes or give IV over at least 5 minutes mixed in a dextrose- containing (e.g., D5W) or saline solution (NS) usually every 6 hours; or as directed by your doctor. The dosage is based on your medical condition and response to therapy.
What is the difference between enalapril and enalaprilat?
Enalapril is the ethyl ester of enalaprilat. It has little pharmacological activity until it is hydrolyzed in the liver to enalaprilat. Enalapril is available commercially as the maleate salt. Enalapril maleate is absorbed better from the gastrointestinal tract in dogs than enalaprilat.
When do you use enalaprilat?
Enalapril is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.
How is Vasotec administered?
The recommended initial dose is 2.5 mg. The recommended dosing range is 2.5 to 20 mg given twice a day. Doses should be titrated upward, as tolerated, over a period of a few days or weeks. The maximum daily dose administered in clinical trials was 40 mg in divided doses.
How do you administer enalaprilat injection?
Administration
- Intravenous (IV): 1.25 mg/dose given over 5 minutes every 6 hours. A clinical response typically occurs within 15 minutes.
- Concomitant diuretic therapy: start with 0.625 mg IV over 5 minutes.
- Conversion from IV enalaprilat to enalapril:
What is Vasotec IV?
Uses for Vasotec I.V. Enalaprilat injection is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.
Can ACE inhibitors be given IV?
All of the ACE inhibitors are prescribed orally, except for enalapril, which can be given intravenously. Enalapril’s IV dosage is initially 0.625 to 1.25 mg every 6 hours. Dosage titration up can be to 5 mg IV every 6 hours. Geriatric dosing should definitely initiate at the lower end of the adult dosing regimen.
What is enalapril IV used for?
Descriptions. Enalaprilat injection is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.
Can you give enalapril IV push?
The dose for pt’s being converted from oral to IV is the same. May also be given IV push over 5 minutes. The dose in hypertension is 1.25 mg every six hours administered intravenously over a five minute period. A clinical response is usually seen within 15 minutes.
When should I take iv enalapril?
For Hypertension: Intravenous (IV): 1.25 mg/dose given over 5 minutes every 6 hours. A clinical response typically occurs within 15 minutes. Concomitant diuretic therapy: start with 0.625 mg IV over 5 minutes.
How are ACE inhibitors administered?
Is enalapril IV push?
Enalaprilat is the active metabolite of the oral prodrug enalapril maleate. Enalaprilat is poorly absorbed orally and requires intravenous administration.
What is the dosage of Vasotec for enalapril?
The dose for patients being converted to enalaprilat injection, USP from oral therapy for hypertension with enalapril maleate is 1.25 mg every six hours. For conversion from intravenous to oral therapy, the recommended initial dose of Tablets VASOTEC (Enalapril Maleate) is 5 mg once a day with subsequent dosage adjustments as necessary.
What is the highest dose of enalaprilat for hypertension?
Stability data: No dosage regimen for enalaprilat injection has been clearly demonstrated to be more effective in treating hypertension than 1.25 mg every six hours. However, in controlled clinical studies in hypertension, doses as high as 5 mg every six hours were well tolerated for up to 36 hours.
How do you administer enalaprilat IV?
For enalaprilat, administer 0.625 mg IV over at least 5 minutes and preferably up to 1 hour every 6 hours. Administer oral and IV doses after hemodialysis.
What is the dosage of Vasotec for hypertension?
No dosage regimen for VASOTEC I.V. has been clearly demonstrated to be more effective in treating hypertension than 1.25 mg every six hours. However, in controlled clinical studies in hypertension, doses as high as 5 mg every six hours were well tolerated for up to 36 hours.