What are potential contraindications to the use of ondansetron?
Contraindications. Ondansetron is contraindicated in patients: known to have hypersensitivity (e.g., anaphylaxis) to Ondansetron or any of the components of the formulation [see Adverse Reactions (6.2)] receiving concomitant apomorphine due to the risk of profound hypotension and loss of consciousness.
What should I monitor before giving ondansetron?
Assess dizziness and drowsiness that might affect gait, balance, and other functional activities (see Appendix C). Report balance problems and functional limitations to the physician and nursing staff, and caution the patient and family/caregivers to guard against falls and trauma.
What should you monitor when taking Zofran?
Zofran’s label advises doctors to perform heart monitoring of people who are taking the drug along with other medications that can also lead to QT prolongation or in patients with: Certain electrolyte abnormalities (such as low potassium or low magnesium) Congestive heart failure.
What are contraindications for Zofran?
ZOFRAN is contraindicated in patients: known to have hypersensitivity (e.g., anaphylaxis) to ondansetron or any of the components of the formulation [see ADVERSE REACTIONS] receiving concomitant apomorphine due to the risk of profound hypotension and loss of consciousness.
Can I take ondansetron with gabapentin?
No interactions were found between gabapentin and Zofran.
Who should not use ondansetron?
Ondansetron is not approved for use by anyone younger than 4 years old. Ondansetron orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).
What are nursing considerations for ondansetron?
Nursing Considerations for Ondansetron
- Observe for the improvements within the gastrointestinal symptoms to take down if the drug therapy is working well with the patients. Symptoms to monitor include reduced incidents of nausea and vomiting and Improved appetite.
- Check for the patient’s motor function.
What must be known before giving Zofran?
Before taking ondansetron, tell your doctor and pharmacist if you are allergic to ondansetron, alosetron (Lotronex), dolasetron (Anzemet), granisetron (Kytril), palonosetron (Aloxi, in Akynzeo), any other medications, or any of the ingredients in ondansetron products. Ask your pharmacist for a list of the ingredients.
Can you take Zofran with antidepressants?
Do not take Zofran (ondansetron) more often than directed. Zofran (ondansetron) may interact with some antidepressants and can cause a serious condition called serotonin syndrome (too much serotonin in the body). Symptoms include confusion, fast heartbeat, diarrhea, and muscle stiffness.
Who shouldnt take ondansetron?
What is the antidote for ondansetron?
There is no specific antidote for ondansetron overdose. Patients should be managed with appropriate supportive therapy.
What is the role of pregabalin in the treatment of post-herpetic neuralgia?
Sabatowski R., Galvez R., Cherry D., Jacquot F., Vincent E., Maisonobe P., et al. . (2004) Pregabalin reduces pain and improves sleep and mood disturbances in patients with post-herpetic neuralgia: results of a randomised, placebo-controlled clinical trial.
Does pregabalin have an adverse effect profile?
After more than a decade of experience with pregabalin, experience and studies have shown that the adverse effect profile of pregabalin is well tolerated for the management of neuropathic pain and other conditions.
Does pregabalin affect the release of synaptic vesicles from cultured hippocampal neurons?
Micheva K., Taylor C., Smith S. (2006) Pregabalin reduces the release of synaptic vesicles from cultured hippocampal neurons. Mol Pharmacol70: 467–476 [PubMed] [Google Scholar]
What is pregabalin?
Used mainly for the management of neuropathic pain, pregabalin is a gabapentinoid or anticonvulsant that was initially developed as an antiepileptic agent.