What causes Scoline apnea?
Suxamethonium (succinylcholine) apnoea occurs when a patient has been given the muscle relaxant suxamethonium, but does not have the enzymes to metabolise it. Thus they remain paralysed for an increased length of time and cannot breathe adequately at the end of an anaesthetic.
Is Scoline still used?
This drug is not often used for planned surgery nowadays, but it is still commonly used in emergency surgery.
What is the action of Scoline?
Mechanism of Action A depolarizing neuromuscular blocking agent, succinylcholine adheres with post-synaptic cholinergic receptors of the motor endplate, inducing continuous disruption that results in transient fasciculations or involuntary muscle contractions and subsequent skeletal muscle paralysis.
What is SUCS in medicine?
Suxamethonium is available as a generic medication. It may colloquially be referred to as “sux”….Suxamethonium chloride.
| Clinical data | |
|---|---|
| Pronunciation | /ˌsʌksɪnɪlˈkoʊliːn/ |
| Trade names | Quelicin, Anectine, others |
| AHFS/Drugs.com | Monograph |
| License data | US DailyMed: Succinylcholine |
How is succinylcholine apnoea treated?
Administration of cholinesterase inhibitors, such as neostigmine, is controversial for reversing succinylcholine-related apnea in patients who are pseudocholinesterase deficient. The effects may be transient, possibly followed by intensified neuromuscular blockade.
Is there an antidote for succinylcholine?
Dantrolene is an effective antidote.
Is suxamethonium a Scoline?
Suxamethonium chloride Injection is an a ultra-short acting, depolarising, neuromuscular blocking agent. It is used in anaesthesia as a skeletal muscle relaxant to facilitate tracheal intubation and mechanical ventilation surgical procedures.
What is the antidote for succinylcholine?
What is Scoline hormone?
What Is Succinylcholine and How Does It Work? Succinylcholine is a skeletal muscle relaxant for intravenous (IV) administration indicated as an adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
What is antidote for succinylcholine?
What is another name for succinylcholine?
Succinylcholine is available under the following different brand names: Anectine and suxamethonium.
Can edrophonium used in succinylcholine apnoea?
Edrophonium 10 mg, given 74 min after succinylcholine, when train-of-four stimulation was characteristic of phase II block, produced partial antagonism which was not sustained. Repeated doses of edrophonium to 70 mg and neostigmine to 2.5 mg did not antagonize or augment the block.