What does Steven Johnson look like?
A red or purple rash that spreads. Blisters on your skin and the mucous membranes of the mouth, nose, eyes and genitals. Shedding of skin within days after blisters form.
What triggers Steven Johnson Syndrome?
Medications most likely to cause Stevens-Johnson syndrome include: Antibacterial sulfa drugs. Anti-epileptic drugs, including phenytoin (Dilantin®), carbamazepine (Tegretol®), lamotrigine (Lamictal®), and phenobarbital (Luminal®). Allopurinol (Aloprim®, Zyloprim®), a drug used to treat gout and kidney stones.
Can SJS be mild?
Skin and mucous membrane involvement initially can be mild or it can rapidly progress. Some individuals may have severe skin symptoms and mild mucosal involvement while others have mild skin involvement and severe mucosal symptoms.
Is Steven Johnson Syndrome itchy?
Some individuals who survive the initial, acute episode of SJS or TEN may experience severe, chronic symptoms. Long-term skin issues can include itching (pruritus), excessive sweating (hyperhidrosis), and abnormal dryness of the skin.
How can you tell the difference between SJS and 10?
The difference between SJS, SJS/TEN overlap, and TEN is defined by the degree of skin detachment: SJS is defined as skin involvement of < 10%, TEN is defined as skin involvement of > 30%, and SJS/TEN overlap as 10-30% skin involvement.
How long does Stevens-Johnson syndrome last?
Even after the reaction stops, it can take weeks or months to recover, and fatigue after leaving the hospital may last for weeks. People who survive SJS or TEN may have long lasting complications. These include dry, discolored skin, hair loss, excessive sweating and loss of fingernails and toenails.
How does Steven Johnson syndrome affect the eyes?
It is more common in children and younger adults, but can develop at any age. Typical ocular problems associated with SJS can include conjunctivitis, scarring of the conjunctiva, inflammation inside the eye (iritis), corneal blisters and perforation, which can potentially lead to permanent vision loss.
What is the survival rate for Steven Johnson syndrome?
When distinguishing patients by severity, the mortality rate at 1 year was 24% for SJS, 43% for SJS/TEN overlap, and 49% for TEN. Several other factors were associated with a high impact on mortality, including recent malignancy and recent infection.
What is the cause of Stevens Johnson syndrome?
An HIV infection. Among people with HIV,the incidence of Stevens-Johnson syndrome is about 100 times greater than among the general population.
What is the treatment for Stevens Johnson syndrome?
Psychiatric support for extreme anxiety and emotional lability
What is the history of Stevens Johnson syndrome?
Stevens–Johnson syndrome (SJS) is a milder form of toxic epidermal necrolysis (TEN). These conditions were first recognised in 1922. A classification first published in 1993, that has been adopted as a consensus definition, identifies Stevens–Johnson syndrome, toxic epidermal necrolysis, and SJS/TEN overlap.